He has experimented with several laser modalities to determine which performs the best in this therapy and on what basis. His experiments and clinical research and experience have shown that the unique physical characteristics of CO2 laser energy when applied to hibernating myocardial tissue provide the most substantial improvements in cardiac function because of the re-remodeling and angiogenic processes that are initiated by the interaction of CO2 energy with the indicated myocardial tissue.
Prof. Klein is an associate Professor in the Department of Cardiovascular and Thoracic Surgery at the Düsseldorf Medical School. Besides valve surgery, he is especially interested in different approaches to myocardial regeneration and revascularisation, such as transmyocardial laser treatment and stem cell therapy for end-stage heart failure. Professor Klein received his MD and PhD at Düsseldorf Medical School, where he specialised in general, vascular and cardiothoracic surgery.